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Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury | Respiratory Research | Springer Nature Link

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They showed that the transcription factor Nrf2, possibly in complexes with other Jun or Maf proteins, was responsible for trans -activating the human GCLC promoter via binding to ARE4 in response to β-NF, pyrrolidine dithiocarbamate, and TBH (Wild et al., 1999